Ursula B Kaiser Selected Research

Precocious Puberty

10/2021	Central precocious puberty: Recent advances in understanding the aetiology and in the clinical approach.
1/2021	Genotype-Phenotype Correlations in Central Precocious Puberty Caused by MKRN3 Mutations.
10/2020	GENETICS IN ENDOCRINOLOGY: Genetic etiologies of central precocious puberty and the role of imprinted genes.
10/2020	Makorin RING finger protein 3 and central precocious puberty.
7/2020	The Peripubertal Decline in Makorin Ring Finger Protein 3 Expression is Independent of Leptin Action.
1/2020	MKRN3 inhibits the reproductive axis through actions in kisspeptin-expressing neurons.
5/2019	MKRN3 Mutations in Central Precocious Puberty: A Systematic Review and Meta-Analysis.
1/2019	DLK1, Notch Signaling and the Timing of Puberty.
1/2019	Evolutionary Conservation of MKRN3 and Other Makorins and Their Roles in Puberty Initiation and Endocrine Functions.
1/2018	Central Precocious Puberty Caused by a Heterozygous Deletion in the MKRN3 Promoter Region.

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Ursula B Kaiser Research Topics

Disease

20	Precocious Puberty 10/2021 - 02/2008
15	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2022 - 10/2003
10	Idiopathic Hypogonadotropic Hypogonadism 11/2014 - 07/2003
9	Neoplasms (Cancer) 01/2019 - 12/2006
5	Infertility (Sterility) 01/2022 - 07/2009
4	Adenoma (Adenomas) 11/2022 - 11/2016
4	Pituitary Neoplasms (Pituitary Adenoma) 01/2022 - 07/2009
4	Pituitary ACTH Hypersecretion 12/2021 - 11/2010
3	Hypothyroidism 01/2019 - 08/2010
3	AIDS-Related Complex (ARC) 02/2015 - 07/2010
3	Kallmann Syndrome (Kallmann's Syndrome) 04/2011 - 01/2010
2	Acromegaly 06/2022 - 01/2021
2	Pathologic Processes 01/2022 - 09/2012
2	Prader-Willi Syndrome (Syndrome, Prader-Willi) 10/2020 - 06/2015
2	Addison Disease (Addison's Disease) 01/2019 - 11/2010
2	Thyrotoxicosis 01/2019 - 12/2017
2	Hypophysitis 01/2019 - 02/2015
2	Delayed Puberty 01/2018 - 06/2015
2	Melanoma (Melanoma, Malignant) 02/2015 - 09/2012
2	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 03/2014 - 08/2009
2	Amenorrhea 03/2014 - 08/2009
1	Malnutrition (Nutritional Deficiencies) 01/2022
1	Sleep Deprivation 01/2022
1	Depressive Disorder (Melancholia) 12/2021
1	Major Depressive Disorder (Major Depressive Disorders) 12/2021
1	Lewis Lung Carcinoma 12/2021
1	Muscular Atrophy (Muscle Atrophy) 12/2021
1	Body Weight (Weight, Body) 07/2020
1	Azoospermia 01/2020
1	Temple syndrome 01/2019
1	Diabetes Mellitus 01/2019
1	Male Infertility (Male Sterility) 01/2018
1	Thyroiditis 12/2017
1	Combined Pituitary Hormone Deficiency 01/2017
1	Craniopharyngioma (Craniopharyngiomas) 01/2017
1	Bicornuate Uterus 01/2016
1	Carcinogenesis 12/2012

Drug/Important Bio-Agent (IBA)

18	Gonadotropin-Releasing Hormone (GnRH)FDA Link 01/2022 - 10/2003
15	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 10/2021 - 10/2011
9	GonadotropinsIBA 01/2022 - 10/2003
9	Proteins (Proteins, Gene)FDA Link 12/2021 - 11/2016
7	KisspeptinsIBA 01/2022 - 12/2006
6	Kisspeptin-1 ReceptorsIBA 01/2019 - 04/2011
5	Hormones (Hormone)IBA 11/2022 - 06/2010
5	SteroidsIBA 10/2012 - 04/2005
4	Growth Hormone (Somatotropin)IBA 06/2022 - 08/2010
4	Messenger RNA (mRNA)IBA 11/2016 - 07/2010
3	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2022 - 10/2003
3	LHRH Receptors (Gonadotropin-Releasing Hormone Receptor)IBA 04/2005 - 07/2003
2	Estradiol (Delestrogen)FDA LinkGeneric 01/2022 - 02/2015
2	Insulin (Novolin)FDA Link 01/2021 - 01/2019
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 11/2016
2	Testosterone (Sustanon)FDA Link 01/2020 - 01/2019
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2019 - 02/2015
2	Immune Checkpoint InhibitorsIBA 01/2019 - 01/2018
2	Follicle Stimulating Hormone (Follitropin)FDA Link 12/2016 - 07/2004
2	Luteinizing Hormone (Lutropin)FDA LinkGeneric 12/2016 - 07/2004
2	Biological ProductsIBA 09/2012 - 02/2008
2	Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1)IBA 12/2009 - 11/2009
1	mahuang-tangIBA 01/2022
1	Oral ContraceptivesIBA 01/2022
1	CarbohydratesIBA 01/2022
1	Dexamethasone (Maxidex)FDA LinkGeneric 12/2021
1	Estrogens (Estrogen)FDA Link 12/2021
1	AndrogensIBA 12/2021
1	pegvisomant FDA LinkGeneric 01/2021
1	Insulin-Like Growth Factor I (IGF-1)IBA 01/2021
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 01/2021
1	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2021
1	Somatotropin Receptors (Growth Hormone Receptor)IBA 01/2021
1	LeptinIBA 07/2020
1	NatestoIBA 01/2020
1	Thyroxine (Levothyroxine)FDA LinkGeneric 01/2019
1	AntibodiesIBA 01/2019
1	Reactive Nitrogen SpeciesIBA 01/2018
1	AutoantigensIBA 01/2018
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018
1	Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)IBA 01/2018
1	glutathione-independent formaldehyde dehydrogenase (formaldehyde dehydrogenase)IBA 01/2018
1	ProlactinIBA 11/2016
1	RNA (Ribonucleic Acid)IBA 11/2016
1	B7-H1 AntigenIBA 11/2016
1	Fumigant 93 (D-D)IBA 09/2015
1	AntralIBA 06/2015
1	IpilimumabIBA 02/2015
1	DioxygenasesIBA 12/2012
1	5-hydroxymethylcytosineIBA 09/2012
1	EnzymesIBA 09/2012
1	CytosineIBA 09/2012
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 09/2012
1	LigandsIBA 10/2011

Therapy/Procedure

11	Therapeutics 11/2022 - 12/2006
2	Drug Therapy (Chemotherapy) 06/2022 - 11/2016
2	Radiotherapy 06/2022 - 12/2021
2	Immunotherapy 01/2019 - 11/2016
1	Vasectomy (Vas Occlusion) 01/2020
1	Aftercare (After-Treatment) 12/2017
1	Hysterectomy 01/2016
1	Precision Medicine 06/2015